At the time of these studies, the roles of reactive oxygen species (ROS) in cells were poorly characterised and information on subcellular compartmentation was at best fragmentary
Luciferase reporter assay Luciferase reporter assays were performed as described previously 82,123
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The study concluded that glutathione improves aerobic metabolism and significantly decreases fatigue-related psychological factors, offering a clear mechanistic rationale for its use in energy-limiting chronic illnesses