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Jain S, Su YH, Su YP, McCloud S, Xue R, Lee TJ, Lin SC, Lin SY, Song W, Steffen JD, Hu CT
GSH is synthesized de novo in the brain by astrocytes and research has demonstrated increased GSH synthesis during oxidative stress-related toxicity in vitro , proposing in vivo synthesis of this antioxidant might be sufficient to not detect significant changes (14)
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Furthermore, Sema4D-Fc, the ligand for PlexinB1, is imported into the cell following treatment with the fluorescently tagged protein (Fig