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1 Introduction Sepsis-associated encephalopathy (SAE) represents a severe complication of sepsis, defined by diffuse brain dysfunction without direct central nervous system (CNS) infection ( Oxidative stress is central to SAE pathogenesis, driven by an imbalance between excessive reactive oxygen species (ROS) production and impaired antioxidant defense systems ( The antioxidant defense system, especially GSH metabolism, is linked to neurodegenerative diseases ( Proteomics and metabolomics enable systematic profiling of protein expression and metabolic signatures

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Each dose draws 0.10 mL, so: 3.00 mL 0.10 mL = 30 doses per vial How long 30 doses lasts depends entirely on frequency which is the whole point of the phase schedule: Practically, roughly one vial per month covers the daily loading phase, and the same vial stretches much further once you drop to maintenance frequency