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The systematic review protocol was registered in the International Prospective Register of Systematic Reviews (PROSPERO), registration number: CRD42024554513 (Available from) (NIHR, 2025)

Physiology, Thyroid

In addition, impaired vitamin D signaling pathways have been indicated in thyroid cancer

Reviews note that most observed benefits occur within commonly studied ranges, while gastrointestinal side effects such as bloating or loose stools become more common as intake increases.12 13 43 44 For that reason, most evidence-based supplement protocols fall within the 24g per day range , which reflects the doses most often studied in humans and balances potential benefit with tolerability.7 Are inositol supplements safe