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All the cells were cultured at 37 C and 5% CO 2

Among the several mechanisms proposed in attributing the ability of PPAR ligand in inhibiting leiomyoma cell growth, Houston suggested that the inhibition was mediated by negative cross-talk between ER and PPAR signaling pathway where the activation of PPAR inhibits ER-mediated gene expression (Houston et al., 2003)

[ref] The glutamate-cysteine ligase (GCL) enzyme interacts with glutamate and cysteine, resulting in the formation of gamma-glutamylcysteine

PMID: 39486178 Int J Mol Sci Tamoxifen Exerts Anticancer Effects on Pituitary Adenoma Progression via Inducing Cell Apoptosis and Inhibiting Cell Migration

In TNBC, anthracyclines often demonstrate limited efficacy due to chemotherapy resistance and notable side effects