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We also thank Frank von Delft and XChem group members, including Lizb Koekemoer, Anthony Aimon, Warren Thomson, Ruben Sanchez Garcia, William Bradshaw, Conor Wild, Mihaela Smilova, Charlie Tomlinson, Romain Talon and the I04-1 beamline scientists for their guidance

Melatonin and puerarin have also been associated with reductions in ovarian cell apoptosis, possibly through modulation of the eIF2/ATF4 and Wnt/-catenin signaling pathway respectively (Ding et al., 2024

In some embodiments, the otic formulation or composition comprises about 30% by weight of the cholesterol

Vitamin B12 is known to support emotional well-being by balancing neurotransmitters and helping to reduce stress and anxiety