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In addition, a recent study assessed the influence of intravenous high-dose NAC (29 g, IV within 2 days) combined with low-dose nitroglycerin (7.2 mg, IV within 2 days) on infarct size in patients with ST-elevation myocardial infarction undergoing percutaneous coronary intervention (PCI)

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SAC, a major organosulfur compound in aged garlic extract, prevented renal damage caused by ROS in cisplatin-treated rats, by limiting cisplatin-induced reduction of glutathione level, Nrf2 expression, and activity of several antioxidant enzymes (catalase, glutathione reductase, glutathione peroxidase) (25)