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Following absorption from the Gastrointestinal tract, paracetamol is metabolised predominantly in the liver where it is conjugated into inactive glucuronide and sulphate conjugates, which are excreted in urine, and toxic N-acetyl-p-benzoquinone imine (NAPQI), which is detoxified by glutathione

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By doing so, the liver is better equipped to handle toxins and keep your body healthy

Decreased levels of glutathione, the major brain antioxidant, in post-mortem prefrontal cortex from patients with psychiatric disorders

After incubation, samples were evaporated again, and residues were resuspended and sonicated in 100 L 50 mM HEPES buffer (pH 7.4)