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As these findings do not directly implicate a specific microbial population, age-dependent reductions in diversity and richness of microbial species, with increased gut permeability and infiltration of toxic microbial metabolites such as LPS and amyloids, likely stimulate peripheral C/EBP-/AEP signaling, and thereby progressive A and NFT pathologies (Chen et al., 2020)

This agrees with Chuah and Thng who used dermoscopy, woods light and microscopy in his study

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A randomized placebo-controlled phase 3 trial of an antisense oligonucleotide, drisapersen, in Duchenne muscular dystrophy