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These increases were reduced in samples from the Protandim diet group

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As the risk of ESRD imposed by RA is relatively higher in relatively young individuals not suffering from any other medical conditions, such as obesity, DM, HTN, DL, and CKD, kidney-protective treatment, such as biologic agents, should be preferentially considered among these patients with RA

Inclusion criteria included that the participants have ASD and be within 35 years of age at the start of, and during the trial period