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Proposed mechanisms of Tesamorelin: Activates GHRH receptors Increases endogenous GH release Elevates IGF-1 production Promotes lipolysis Reduces visceral adipose tissue Why Tesamorelin is unique: Unlike most weight-loss therapies, Tesamorelin appears particularly effective at reducing visceral fat the deep abdominal fat surrounding internal organs that is strongly associated with insulin resistance, cardiovascular disease, and metabolic syndrome

About 50% of hyaluronic acid is present in the skin and is also present in internal organs

Shift of the cellular oxidation-reduction potential in neural cells expressing Bcl-2

Dietary Changes: A diet rich in vitamin C, antioxidants, and glutathione can support skin brightening from within

PMID: 36539421