There is also recent data which suggest that genetic alterations of the receptor by which B12 is transported into nerve tissue and the brain, may lead to a lower B12 uptake
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26 A review of 17 clinical studies of various trial designs, including pro- and retrospective, concluded that B12, particularly subcutaneously injected mB12 [methyl-B12], improves metabolic abnormalities in ASD along with clinical symptoms
As with any medical treatment, it's important to weigh the potential benefits against possible side effects and costs
This benefits people with low stomach acid (including many people over the age of 50) or those who take acid blockers such as Pepcid or Zantac, or proton pump inhibitors such as Prevacid, or Prilosec, who are at an increased risk for B-12 deficiency