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ARPE-19 viability was evaluated as previously described [23]

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Complex I inhibition results in an enhanced production of ROS, which, in turn, will inhibit complex I

Conversely, in patients with anorexia nervosa, even supra-physiologic GH doses (mean maximum daily dose: 1.4 mg/day) may not be sufficient to normalize IGF-I levels (61) indicating the important role of hepatic GH sensitivity in successful IGF-I generation

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