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Most of the studies analysing the effects of HTP have been conducted by manufacturers, but there is a growing body of independent research on HTP and more than 400 non-industry studies have been published since 2024

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Of these, four studies showed statistically significant differences between the intervention and control groups 17,20,22,24 , while one did not reach statistical significance

The number of past year initiates and the percentage of people using smokeless tobacco for the first time among those at risk for initiation were higher among adolescents and young adults than among adults aged 26 or older (Figure 4)

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