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In our meta-analysis, we performed meta-regression to minimize confounding factors, but due to the insufficient number of studies adjusting results to factors such as socio-economic status, level of education and alcohol consumption, we were only able to use age, gender and year of publication as moderators

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Landmark studies have shown that lung cancer mortality was reduced by lung cancer screening using chest computed tomography in a high-risk population with a minimum of 15 to 30 pack-years of smoking history [12, 13]

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