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(1997) reported that IGF-1 LR3 increased tumor growth in tumor-bearing catabolic rats

Cold exposure narrows blood vessels, causing numbness in fingersespecially with Raynauds

These include people with active cancer (any type), people who are pregnant or planning pregnancy, anyone with a known allergy to tesamorelin or mannitol (an inactive ingredient), and people with major problems of the hypothalamus or pituitary gland (the brain area that controls hormone release)

Local injection near the injury site concentrates the peptide where its needed

That success has raised legitimate curiosity about what other peptides might offer