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Extensive heterogeneity in somatic mutation and selection in the human bladder

However beyond even the needs in sessile multicellular plants, multicellularity in animals is critically dependent on advanced cell-cell communication, and likely required a quantum leap in signaling

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Figure 3 4.2.2 Macrophages In RA, activity imbalance between pro-inflammatory M1 macrophages and anti-inflammatory M2 macrophages elicits inflammation and autoimmunity in the synovium, leading to joint damage (134)

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