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Theyre more likely to cause discomfort, inflammation, or even pain during or after the injection, which can make regular dosing unpleasant and less sustainable

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[2] Once administered intramuscularly, B12 is gradually released into the bloodstream and transported to the liver, where approximately half of the body's total B12 stores are held

This is why aliquoting, minimizing air exposure, and following recommended storage temperatures are critical after reconstitution

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