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The lower arginine in LC patients as reported in acute COVID-19 (57) can be related to increased frequency of CD71+ erythroid cells (CECs) expressing arginase-I and II (58, 59) or the pathology associated with the effects of the virus on the endothelium (60)

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However, whether the universality of this criterion is limited by ethnicity, region and gender remains to be further studied

Nuclear receptor LXR controls fitness and functionality of activated T cells