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5.5 Conclusion and future direction Recognizing the limitations of conventional delivery routes in targeting the CNS, IN administration provides a non-invasive alternative that not only bypasses the BBB but also avoids hepatic first-pass metabolism

Redox Signaling , 2013, vol

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doi: 10.1016/j.mce.2017.06.002 224 MarquesPSkorupskaiteKGeorgeJTAndersonRA

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