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Indeed, discussions about the role of the blood-brain barrier in epilepsy have continued for decades (12, 13)

Interestingly, greater benefits were seen in those with high compared to low homocysteine concentrations at baseline, suggesting the importance of lowering homocysteine levels in prevention of brain atrophy and cognitive decline (91-93)

Briefly, image preprocessing involved image segmentation, registration and normalization to Montreal Neurological Institute (MNI) space using SPM12

Plant Biotechnol Rep 5(3):225234 Al-Quraan NA (2015) GABA shunt deficiencies and accumulation of reactive oxygen species under UV treatments: insight from Arabidopsis thaliana calmodulin mutants

Zinc repletion reduces promoter accessibility, thereby limiting IL-1 production under basal conditions, although it can still be induced by stimuli (danger signals) such as LPS [510]