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Ann Dermatol Venereol

US25SEMO03449 December 2025 SOURCE NOVO NORDISK INC.

Additional mitochondrial proteins such as glycine amidinotransferase, the redox-sensitive chaperone PARK7, peroxiredoxin 6, and the voltage-gated ion channel VDAC2 were found to be modified by NAPQI in 3D cultures of human hepatocytes and nonparenchymal cells29

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Knockout of RNA methyltransferase 4 or overexpression of RNA demethylation-related genes can weaken the upregulation of m6A in induced pluripotent stem cells and inhibit ferroptosis [75]