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383 Treg cells play a critical role in the immune system by suppressing the immune response and maintaining immune tolerance, whereas Th cells are involved mainly in the regulation and promotion of the immune response
Inhibitors targeting enzymes such as adenosine phosphate transferase, non-ribosomal peptide synthase (NRPS), polyketide synthase, and NRPS-independent siderophore synthases impair microbial iron uptake and enhance host-mediated clearance (Petrik et al., 2012
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