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Injecting close to the affected area is believed by some to provide more localized effects, though systemic distribution occurs regardless of injection site

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This approach requires precise dilution and technique, and is typically only performed by experienced practitioners

238 These more water-soluble lipoproteins can be delivered to tissues throughout the body, including into arterial walls where one of these proteins, ApoB, plays a critical role in atherosclerotic plaque formation

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