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[10] [11] The lack of IGF-1 (or inhibition of IGF-1R) causes impaired cellular morphogenesis to occur, which prevents lipids from being secreted in some keratinocytes that build out the lamellar bilayer of the skin at the SC-SG interface around the follicles

Tirzepatide and retatrutide stay within the incretin/glucagon family

55 MollerN.JorgensenJ

Rather, it reflects an indirect effect mediated through alterations in the skin's microbial ecosystem

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