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Our research-grade NAD+ is produced under strict quality-controlled laboratory conditions and supplied as a stable lyophilized formulation to ensure maximum purity, consistency, and reproducibility across experimental applications

Tissue plasminogen activator (tPA), is a naturally produced protein in endothelial cells that functions as a serine protease, catalyzing the conversion of plasminogen to plasmin, which acts as a key player in fibrinolysis

Because B12 is absorbed in your colon is what my doctor told me

In neuronal senescence model studies, the active ingredient of the product can cross the blood-brain barrier (and act directly on neurons in vitro), increase NAD+ levels in nerve cells, protect mitochondrial function, reduce neuronal apoptosis, and promote the synthesis and release of neurotransmitters (such as dopamine and acetylcholine), thereby improving signal transduction in nerve cells

Your body doesnt make B12 on its own