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Activation of endosomal TLR7/8 during SARS-CoV-2 may increase the inflammatory response resulting in severe and potentially lethal immunopathological effects in COVID-19 patients as consequence of the simultaneous release of pro-inflammatory cytokines and chemokines

Generative AI statement The author(s) declared that generative AI was not used in the creation of this manuscript

To answer the first question, we transplanted tumors lacking the ability to produce GSH (Gclc-KO) into wild-type mice and, surprisingly, the tumors grew normally

This can be the most dangerous stage as seizures and other health complications may arise

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