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It's which biological system you're trying to optimize

Moreover, nanotechnology allows for the co-delivery of multiple therapeutics, synergizing with other therapies, and simultaneously disrupting complementary metabolic pathways to overcome compensatory mechanisms and prevent drug resistance [264, 265]

When activated, Nrf2 disassociates from its repressor protein KEAP1 that reacts with oxidative radicals, translocates to the nucleus, binds to antioxidant response element and induces the transcription of defensive genes

doi: 10.1016/j.ejmech.2024.117015 24 HussainSGuptaGShahwanMBansalPKaurHDeorariMet al

Hair Transplant: A surgical procedure considered a permanent solution for suitable candidates