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The results showed no significant differences in any of the indicators, indicating that FOXO4-DRI treatment did not adversely affect liver or kidney function or cell viability in mice (Supplementary Figures S2AC)

Supported by a long-standing Program Project Grant now in its third cycle, MCG researchers have shown that blocking the aryl hydrocarbon receptor (AhR) a protein activated by environmental toxins and metabolic byproducts can significantly improve bone mass and preserve muscle function in aging mice