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CJC-1295 with DAC suits a narrower set of situations where sustained elevation is specifically desired, and it comes with the trade-offs of departing from pulsatile physiology

It works synergistically with neurotrophic peptides

AsA scavenges OH, SOR and 1 O 2 directly and reduces H 2 O 2 to water through ascorbate peroxidase reaction 69

In mice that have combined KO of ghr and igf1 , the growth deficiency is significantly more severe than in each individual KO (322), indicating that GH has growth mediating effects that are independent of IGF-1

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