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They work by inhibiting the production of melanin, the pigment that gives the skin its color

Genes and proteins involved in adult cholestasis and their clinics and laboratory results are summarized in Table 2

GPx2 The selenium-dependent glutathione peroxidase GPx-GI encoded by GPx2 is highly expressed in gastrointestinal epithelial cells and occasionally in breast tissue [94]

L-GSH supplementation for 3-months resulted in a significant increase in the levels of IFN- in the PBMCs ( Figure 5B ), but not in plasma ( Figure 5A )

The methionine and choline-deficient diet (commonly applied in mice and rats) and choline-deficient L-amino-defined diet rapidly induce NASH, but fail to reproduce the pathophysiological response corresponding to clinical observations [125, 126]