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Once GSH is depleted, ROS and reactive nitrogen species escalate, leading to increased oxidative stress, mitochondrial dysfunction, and DNA damage

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Then, without warning, he will nervously search for a cigarette, abandon his search in the middle of it (wise, since English cigarettes are bad), and seize his head in his two hands, twisting it from side to side and lowering his head near the board so the he can have a convenient recepticle if ever his head does come off