United States: Dihexa is not classified as a prescription drug, dietary supplement, or approved therapy
Patients with ALT levels rising above 3 times ULN had acetaminophen stopped, but enzyme levels continued to rise for a few days as in this patient, whose ALT level was 575 U/L 5 days after stopping drug, and at a point that acetaminophen levels were undetectable
However, the essential oil contains coumarins, which can cause phototoxicity in humans and have been linked to tumor formation on the skin and foregut of mice
Although cholesterol is essential for certain cell functions, there may be a role for atorvastatin in preventing some dementias (especially in patients with certain metabolic syndromes or with ApoE4 mutations), with possible reduction of -amyloid production, reduction of vascular inflammation, protection of endothelial cell function and reduction of brain ischemia (67)
VAS, visual analog scale