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Both represent the "next generation" of targeted therapy that moves beyond simple receptor agonism

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More precisely, this study is the first to reveal that induction of autophagy exerts a protective role against the intrinsic metabolic stress and attempts to antagonize degenerative processes in normal appearing vitiligo skin, where melanocytes and fibroblasts are already prone to premature senescence

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Franke H, Fryer G, Ostelo RW, Kamper SJ