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Other than the generation of ROS from CQDs, the antibacterial mechanism of CQDs have been recorded such as DNA binding, membrane destabilisation, physical and mechanical damage and inhibition of bacterial metabolism

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In contrast, in strains expressing low levels of mRNA, gdhA P2 was not active due to the weak expression of gdhR , an associated regulatory gene, as a result of the insertion of the miniature neisserial element (nemis also known as Correia element) downstream of gdhR that destabilizes its mRNA

The standard dose is 1 mL, which is 1000 mcg of Vitamin B12

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