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Thorne is certified by NSF International, an organization that tests supplements for quality and potency and inspects manufacturing facilities, and the Therapeutic Goods Association (TGA), a regulatory agency run by the Australian Government Department of Health

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In September 2023 the FDA placed BPC-157 in Category 2 of its 503A interim bulk-substances policy, citing immunogenicity and peptide-characterization concerns, effectively excluding it from the 503A compounding bulk-substances list