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Purified rSmGST showed high activity at pH 6.5 and optimum temperature at 25C

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Under physiological conditions, mitochondria localized near the apical membrane form a buffering zone that restricts the spread of Ca 2+ signals from the subplasmalemmal region to the cell interior, thereby protecting PACs from Ca 2+ -induced injury (16)

Eligible patients were randomized in a 1:1:1:2 ratio into one of four treatment groups: GIC-1001 at doses of 250 mg, 375 mg, or 500 mg, and a matching placebo group

Additionally, cancer cells carrying a mutant TP53 protein exhibit increased CHAC1 levels and show greater resistance to ferroptosis (Leu et al., 2019