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While brands such as Manchester are known for offering everything from strong reds to menthol capsules, Esse focuses more on a lighter draw, refined presentation and flavour-led options

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ACE2 gene expression in airway epithelium is upregulated by tobacco smoking (Leung et al., 2020), possibly through the 7 subtype of the nicotine acetylcholine receptor (Russo et al., 2020)