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Walter de Gruyter, 1975

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2011, titled Tobacco addiction and psychological co-morbidities. Physically, nicotine affects the brains reward system, releasing neurotransmitters like dopamine, which leads to cravings and withdrawal symptoms when tobacco use is reduced or stopped

For tobacco and marijuana smoke, respectively, 4350 and 2575 different compounds are detected, of which, 670 and 536 (231 in common) are tentatively identified, and of these, 173 and 110 different compounds (69 in common) are known to cause negative health effects through carcinogenic, mutagenic, teratogenic, or other toxic mechanisms

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