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This structural feature gives the peptide exceptional stability and resistance to breakdown by digestive enzymes, setting it apart from most other therapeutic peptides

However, some studies have found increased GABA concentrations and GABA/creatine ratios in the left dorsolateral prefrontal cortex of adult ASD patients, which may support the excitation/inhibition (E/I) imbalance hypothesis, suggesting enhanced inhibitory function in this region (132, 133)

the trypsin activity was then neutralized with fetal bovine serum (FBS)

It takes approximately this long for daily dosing to reach a pharmacokinetic equilibrium, where the rate of drug accumulation from daily dosing matches the rate of elimination