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Cell culture studies demonstrate increased expression of synaptic proteins including PSD-95, synaptophysin, and synapsin following Dihexa treatment, confirming molecular mechanisms underlying the observed synaptogenic effects

Growth factor receptor-bound protein 2 (GRB2), an adaptor protein, binds to the receptor and recruits Son of Sevenless (SOS), a guanine nucleotide exchange factor (GEF)

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