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The Institute of Medicine (IOM) report Marijuana and Medicine: Assessing the Science Base has said epidemiological data indicate that in the general population marijuana use is not associated with increased mortality. That roughly translates to cannabis is not directly related to any increase in the chances of death or has a significant impact on your lifespan

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These initiatives emphasize the long-term implications of smoking, including chronic diseases and reduced life expectancy, which impact the willingness of adult smokers to invest in higher-end products

part F, supplemental guidance for inhalation risk assessment