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In addition, transforming growth factor-1 (TGF-1), a potent fibrogenic protein, is known to upregulate astrocyte synthesis of proteoglycans causing severe gliosis (Yin et al., 2009

An overview of thestomach-stress-organoprotection hypothesis and beneficial effects of BPC Small Vessels, Big Trouble: How Vascular Disease Drives Dementia In this 161st episode I unpack vascular dementia what causes it, how it differs from (and often overlaps with) Alzheimers, and the brain and vascular mechanisms that drive cognitive decline

Alcohol depresses the central nervous system and causes neurological and behavioral changes

5.2 Rheumatoid arthritis In RA, TNF- serves as a key mediator of ferroptosis through iron-dependent lipid peroxidation