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FIGURE 1 Transcriptional regulation of eNOS The NOS3 gene is located on chromosome 7 (7q35-36) and is regulated by a promoter region containing binding sites for multiple transcription factors, including Krppel-like Factor 2 (KLF2), Specificity protein 1 (Sp1), Specificity protein 3 (Sp3), Ets1, mothers against decapentaplegic homolog-2 (Smad2), and Nuclear factor erythroid 2-related factor (Nrf2), among others (Karantzoulis-Fegaras et al., 1999

10.1007/s10545-010-9061-2 66 HuS.ZhangC.QianT.BaiY.ChenL.ChenJ.et al (2021)

Although glutamine is found naturally in high protein foods, under certain conditions such as stress, chronic inflammation and intense exercise there is an increased demand for glutamine