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As described, the cGAS-STING pathway is a canonical in innate inflammatory stress responses, not only within neurons and glial cells of the CNS but also across a broad range of peripheral tissues, contributing to diverse pathological contexts such as cancer (Chakraborty et al., 2024

[Google Scholar] [PubMed] Timn-Zapata J, Laserna-Mendieta EJ, Pineda-Tenor D, Agudo-Macazaga M, Narros-Cecilia C, Rocha-Bogas MJ, Ruiz-Martn G, Gmez-Serranillos M (2011)