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SantamaraEAvilaMALatasaMURubioAMartn-DuceALuSCet alFunctional proteomics of nonalcoholic steatohepatitis: mitochondrial proteins as targets of S-adenosylmethionine

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Jamalpoor A, van Gelder CA, Yousef Yengej FA, Zaal EA, Berlingerio SP, Veys KR, Pou Casellas C, Voskuil K, Essa K, Ammerlaan CM, Rega LR, van der Welle RE, Lilien MR, Rookmaaker MB, Clevers H, Klumperman J, Levtchenko E, Berkers CR, Verhaar MC, Altelaar M, Masereeuw R, Janssen MJ (2021) Cysteamine-bicalutamide combination therapy corrects proximal tubule phenotype in cystinosis

Glutathione acts as a protective shield against these aggressors

Although this GST was also present in a near isogenic susceptible line, evaluation of corresponding transcript accumulation revealed that GST gene expression was significantly induced only in the BNYVV-resistant line (Larson et al., Rice tungro spherical virus (RTSV) demonstrated the induction of at least twenty GST genes in both interactions