Free Radic Res 54(1112):841847 Huang H et al (2023) Genetically engineered mesenchymal stem cells as a nitric oxide reservoir for acute kidney injury therapy
et al., NNMT regulates cellular metabolism through NAD and methyl donor balance, Nature Chemical Biology, 2013
doi: 10.1016/j.jconrel.2013.06.023
According to some embodiments, the therapeutic amount of the Withania somnifera active ingredient is in an amount at least about 10 mg, at least about 9.8 mg, at least about 9.6 mg, at least about 9.4 mg, at least about 9.2 mg, at least about 9.0 mg, at least about 8.8 mg, at least about 8.6 mg, at least about 8.4 mg, at least about 8.2 mg, at least about 8.0 mg, at least about 7.8 mg, at least about 7.6 mg, at least about 7.4 mg, at least about 7.2 mg, at least about 7.0 mg, at least about 6.8 mg, at least about 6.6 mg, at least about 6.4 mg, at least about 6.2 mg, at least about 6.0 mg, at least about 5.8 mg, at least about 5.6 mg, at least about 5.4 mg, at least about 5.2 mg, at least about 5.0 mg, at least about 4.8 mg, at least the Withania somnifera extract is in a form of a powder, a liquid solution, a suspension, a dispersion, an emulsion, a tablet, a pill, a capsule, a sustained release formulation, or a delayed release formulation

Myostatin expression, lymphocyte population, and potential cytokine production correlate with predisposition to high-fat diet induced obesity in mice