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This prevents both over-humidification and drying out, issues that can significantly impact flavor and usability

Data extraction For each brands website, we coded whether there was information on: nicotine concentration (recorded if a numerical value was provided, such as 5% nicotine)

Selecting exposure categories Cumulative exposure in pack-years was the measure of exposure used for COPD and all cancer outcomes except for prostate cancer, to reflect the risk of both duration and intensity of current smoking on these outcomes

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Chemicals People who smoke increase their risk of dying from lung cancer 22 times more than non-smokers and from bronchitis and emphysema 10 times more