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These include chemical modifications (e.g., oxidation, sulfonation), physical treatments (e.g., ultrasonication, thermal processing), biological methods (e.g., enzymatic or microbial incorporation), and functionalization strategies (e.g., grafting with amines, peptides, or silanes), as illustrated in Figure 5

PMID: 29 YuXLiWLiZWuQSunS

Common injection sites: For Intramuscular (IM): Upper arm (deltoid) Outer thigh (vastus lateralis) often the easiest self-injection site Upper outer gluteal muscle usually requires assistance For Subcutaneous (SQ): Abdomen (at least 12 inches away from the navel) Outer thigh Back of the upper arm What are the side effects

Min Y, Yang H, Wang X, Xu C

(2002) Proc Natl Acad Sci USA