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Autophagy inhibition in those tumors affects multiple aspects of cancer metabolism such as lipid metabolism (233), amino acid recycling (234) and nucleotide homeostasis (235), making it a promising therapeutic strategy for RAS-driven cancers

Arch Biochem Biophys 523: 95102, 2012 [DOI] [PMC free article] [PubMed] [Google Scholar] 2.Akoumianakis I

Furthermore, PA inhibited the nuclear localization of p-STAT3, indicating its potential to inhibit the proliferation and metastasis of gastric cancer cells by suppressing the JAK2/STAT3 immune signaling pathway

Although, lanosterol and 25-hydroxycholesterol have shown promising results in preventing and treating cataracts by dissolving lens crystallin proteins, certain researchers have doubted these effect

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